Abstract: Addressing the limitations of traditional acoustic metamaterials—such as single-frequency noise control and interference with airflow—this paper proposes an acoustic metamaterial structure that integrates the Helmholtz resonance effect and the Fabry–Pérot resonance effect, enabling effective noise attenuation within a specific low-frequency range. Simulation results show that, within the 500 Hz frequency range, the acoustic metamaterial exhibits two transmission loss peaks. Subsequently, the influence of structural parameters on resonance frequencies was analyzed. The results indicate that the second resonance peak frequency is negatively correlated with the channel length of the Fabry–Pérot resonator cavity, whereas the first resonance peak frequency is negatively correlated with the height of the Helmholtz resonator cavity and positively correlated with the neck length of the Helmholtz resonator. Finally, an experimental testing platform was established to evaluate the performance of the designed acoustic metamaterial. Measurements show two transmission loss peaks at 221 Hz and 384 Hz, which agree closely with the resonance frequencies predicted by finite element simulations and transfer matrix method (TMM) theory. The transmission loss at these resonance peaks exceeds 20 dB.