Abstract: For the complex sound field environment in the cabin of a certain turboprop aircraft, this article summarizes the research work on the construction of a multi-channel noise active control system and the verification of the noise reduction effect. Based on the spectrum analysis and distribution characteristic analysis of the measured data in the cabin of this turboprop, a multi-channel noise active control system with 24 channel inputs and 16 channel outputs is built, which takes the key peak frequency as the target frequency. Moreover, a comprehensive verification platform for the noise reduction effect of turboprop aircraft similar to the real environment is built in a semi-anechoic chamber to verify the noise reduction effect of the system. The results show that the system can reduce the sound pressure level at key frequencies by 11.1 dB, indicating that the system’s noise reduction effect is significant and effective.