Abstract: An acoustic Doppler current profiler (ADCP) system based on TMS320C6748 and Spartan-6 is designed for accurate flow measurement under the condition of high sediment concentration. DSP is used to communicate with upper computer, control system, interact with FPGA, receive peripheral data and process signal data. FPGA is used to modulate the measured signal and receive acquired signal. In order to verify the feasibility and accuracy of ADCP system in the high sediment concentration environment, a flow measurement test is carried out in the Yellow River, where the survey vessel is used to install ADCP, which accesses GPS data and Echo sounder data by DSP. Test results show that, in the hydrological environment with sediment concentration of 15.5 kg·m^-3, the ADCP system could measure the flow normally and stably, the relative error of flow measurement result is only 1.01%, which meets the requirements of high precision flow measurement system.