Abstract: The acoustic resonance of wheel air chamber is an important contribution to the interior noise of car. The resonator is an effective control mean to the acoustic resonance. However, it is complicate and tedious to evaluate the noise reduction effect of resonator by wheel vibration measurement and vehicle road test in its development process. A set of acoustic pipe measurement method is proposed in this paper. Its measurement principle, test platform design, key techniques and measurement evaluation method are described. Compared with vibration measurement and road test, the results show that the acoustic pipe measurement method is reasonable, simple, accurate and reliable.