Abstract: Personalized three-dimensional (3D) head models have important applications in head-related transfer function (HRTF) and virtual auditory display (VAD). Optical scanning is a common method to obtain 3D head models, but the deviations of different optical scanning methods and their effects on HRTF are not clear. In this paper, the self-designed 3D head model served as a reference model MO (baseline), and the 3D-printed fabricated model was used as the scanning object. Three representative optical scanning devices (handheld red laser scanner HandySCAN 300, handheld white light-emitting diode (LED) scanner Reeyee Pro 2X, and infrared laser iPhone 12 cell phone) were selected to scan and obtain the corresponding models MH, MR, and MI. To evaluate the surface accuracy of the newly acquired models, the color-coded mapping of the graphical deviations between the models and the root mean square (RMS) values of the deviation distances were compared. Further, the HRTF spectral errors between models were compared to analyze the effect of model accuracy on HRTF data. The results showed that the graphical deviations were mainly concentrated in the partial details of the auricle, and the HRTF universal errors mainly appeared in the high frequencies. In comparison, model MH is the closest to MO, with surface errors basically within ±0.40 mm, and HRTF spectral errors exceeding 3.0 dB occur only in the frequency band above 8 kHz, and such errors are observed only in a few spatial directions. The surface errors of the models MR and MI compared to MO reach about −0.90 mm to 1.90 mm and −1.20 mm to 3.20 mm, respectively, and the HRTF spectral errors above 8 kHz exceed 3.0 dB in most directions. The study provides a reference basis for the selection of 3D head scanning modalities.